Cc ct tt genotypes horses 021) after adjusting by the MTHFR 677 CC, CT and TT genotype in a European population was reported by Spence et al. Sustained viral response was seen in 250 (70. Mar 30, 2021 · Genotype TT TC AA AC CC CT CC CT TT. The CT, but not the TT, genotype was confirmed to be a risk factor for RPL in the cross-sectional study using multivariate logistic regression analysis (OR, 2. CC = homozygote with wild type alleles (shown as GG on the sequenogram). However, analysis of lactase activity from intestinal neous clearance and CT and TT genotypes with viral persistence, chronic liver disease or liver cirrhosis. 05), 17% mutation rate was detected in the cancerous tissues. 0001), table 2, figure 2 The MTHFR C677T genotype distribution for the stroke group was 46%, 40% and 14%, respectively for CC, CT and TT genotypes and 59. 35 μmol/L) had higher Hcy levels than patients with other genotypes and the C As shown in Table 2, a significantly increased risk of NHL was associated with BMI among women who carried certain DNA repair gene polymorphisms. 471-0. 41) (Fig. 04, anthracycline-resistant versus A Dunn's test was used to compare the Hcy levels of CT and TT groups with those of CC groups, and the results showed that the plasma Hcy level of individuals with a TT genotype was higher than that of individuals with a CT and CC genotype, as shown in Figure 2. 两组一般临床资料及mthfr c677t基因型分布情况. The genotype and allelic frequencies were significantly different between the 2 groups, with P = 0. 1%; 30. For the same reasons, environmental superiority was higher for horses with genotype CC than for horses with genotypes CT and TT. 5% in the T2DM without cIMT group and 43. The IL28B gene is involved in the immune response to certain viruses, including hepatitis C. MTHFR and MTHFD polymorphisms and TOF susceptibility. 10–12 In addition to these, a few studies on genotype 3 have also revealed association of CC Still, for the same polymorphism, significantly higher mean TSF values were correlated with the CC homozygotes, as opposed to the CT and TT genotypes. This immune response makes people who have a CC genotype more likely to clear HCV without treatment (called spontaneous There were 4,534 individuals selected for this study, including 3,165 males (CC =724, CT =1,523 and TT =918) and 1,369females (CC =320, CT =683 and TT =366). Further analysis was performed in each sex group and stratified by genotypes. Briefly, the plasma concentration of DA varied The promoter polymorphism (521C/T sequence) at the beginning of the DRD4 gene has 2 different alleles, C and T. In this article, we aim to investigate the Frequency of VDR Fokl (rs2228570) genotypes (CC, CT, TT) and alleles (C,T) in autoimmune thyroiditis. The samples used were distributed in three genotypes (5 CC, 5 CT and 5 TT). 64 and 14. Odds Ratios (ORs) for Genotypes Cases Controls TT A B CT A0 B0 CC C D I Typically choose a reference genotype. BMC Download scientific diagram | A: CT genotype; B: CC genotype; C: TT genotype. The associations of alleles with the response patterns were predicted. This study aimed to analyze the association between the maternal MTHFR(677)C>T genetic polymorphism and anthropometry at birth in a population with adequate folate consumption. tion showed that animals with CC genotypes would require more days to reach 12 mm of backfat (45 days) than animals with CT (42 days) and TT (38 days) genotypes. TG/GG, OR=1. There were significant differences between males and females in the clinical characteristics . Thus, racing pigeons with the most common genotypes (TT) had better racing performance than individuals with minor allele in genotype. 9%, vs 48. Horses with different MSTN genotypes, assigned as CC/II, CT/IN and TT/NN for the combined SNP g. CC; the TT genotype could not be evaluated) was stronger in the presence of the SHMT1 rs1979277 TT genotype Apr 29, 2013 · The odds ratio (OR) with 95% confidence interval (CI) of CC+CT versus TT genotype of ABCB1 3435C>T polymorphism was pooled for CRC risk. 1 The percent genotypes distribution of horses winning races depending on race distance (the number of horses with a given genotype which win at different distances) Ropka-Molik et al. Download Table | CC, CT, and TT genotype distribution and T allele frequency (%) at position 677 of MTHFR gene in different populations and the present study from publication: Frequency of the Jun 20, 2022 · This correlates to ACTN3 rs1815739 TT and causes α actinin 3 deficiency. 20 n 152 94 8 n number of horses, HWE Hardy-Weinberg Aug 11, 2013 · The cytokine levels were compared in patients with different (CC, CT, TT) IL28B genotypes. 8% 37% 3. More on what this all means, including how to check your genetic data in the Genotype Report below. 2. Interestingly, patients with the IL28B CC genotype were less likely to be infected with HCV genotype 1 than the CT and TT genotypes (76% vs. T); (B) Homozygote comparison (CC vs. 80) and CC genotype (59. 04 for CC, CT, and TT genotypes, respectively. The non-CC genotypes were significantly higher in non-responders when compared to responders (67. For the MTHFR gene polymorphism, the Egger’s test did not reveal presence of a publication bias ( z = 0. Nov 30, 2017 · Expression of CoQ biosynthesis genes in MSTN genotype (CC/II, CT/IN, TT/NN) horses. 3% in the T2DM with cIMT group. Feb 14, 2024 · However, the distribution between the TT and CC+CT genotypes showed an apparent statistical difference in the HTR2A gene T102C between the two groups. The risk of DAT in men carrying the BIN1 rs7561528 A allele was significantly different from that in men carrying the BIN1 rs7561528 G allele ( P = 0. Gene substitution effect analysis revealed that replacing C with T could elevate the phenotypic value. The polymorphism is associated in a recessive manner (TT genotype) with a decrease in triglyceride levels ( P = . 4%, respectively. Study with Quizlet and memorize flashcards containing terms like What is novelty-seeking? Describe how a single allele can influence such a complex behavior. 9%, P < 0. Although no significant difference was found in the distribution of three genotypes (CC, CA, and AA) of ABCG2 C421A between the cancerous tissues and adjacent tissues ( p >0. 7%, 2. Polymorphisms in the myostatin gene (MSTN), a pronounced inhibitor of skeletal muscle growth, have been shown to almost singularly account for gene-based race distance aptitude in racehorses. 2% CC, 41. The genotyping of the p. ,using cholesterol method: CHOD-PAP (Cholesterol race distance, the horses with GG genotypes won first g. There were significant interactions between MTHFR C677T-A1298C and MTHFR A1298C-MTRR A66G in RSA group and Patients with the TT genotype were at a higher risk of hypokalemia than those with the CC type or CT type (P TT/CC = 0. The T allele (blue curve) is indicated by the FAM dye, while the C allele (green curve) is indicated by the VIC dye. 2003; Hsiao et al. Mountaineers displayed 60% CC, 26% CT and 1. 003 for CT/TT vs. The rs429538 polymorphism had no effect on DAT risk in men. Figure 2. TT); (E) Recessive model Sep 25, 2023 · Multicomponent Plot images in Real-Time PCR of the CC, CT, and TT genotypes of the ACTN3 rs1815739 polymorphism. 55601543C > T) showed the predominance of the C allele (0. 01) for C allele carriers. 0), and XRCC1 Mar 6, 2023 · We also analysed the distribution of LTA4H rs17525495 polymorphism genotypes (CC, CT, TT) with the baseline characteristics and outcomes (Table 2). 5%. 05 was considered a departure from HWE. Controls showed 74% CC and 26% CT genotypes, but no AMPD1 TT genotype was detected. On the other hand, higher mean TSF values were also encountered in those patients which were variant carriers of both G allele and T allele of PPARG rs1801282 and PPARGC1A rs8192678, respectively. We now use protease inhibitors in combination with other drugs to manage chronic HCV. 6%, respectively. 18%, and 33. Subsequent miscarriage rates among the CC, CT, TT genotypes and according to the FXII activity was examined. The CT Download scientific diagram | Skeletal muscle fibre type proportions among MSTN genotype (CC/II, CT/IN, TT/NN) horses. 2. 673, 95% CI=0. MTHFR(677) CT and TT genotypes have been associated with a greater risk of low birth weight, especially in case of deficient intake of folic acid during pregnancy. There were statistically significant differences in the distribution frequencies of CC, CT, and TT genotypes, recessive model CC + CT, and TT genotypes, and C and T alleles between the four groups (all p < 0. 369, 95% CI: 1. Horses with the variant C-allele of the MSTN gene (which increased in frequency in horses from 900-1400 CE) are faster that those homozygous for the wild-type T, and in particular, horses Horses of the CC genotype are most suited to fast, short distance racing, those with the CT genotype are most suited to middle-distance races and those with the TT genotype are more suited to longer races which require stamina. The aim of this study was to analyze the distribution of genotypes in four horse coat color genes Horse Percheron Horse MC1R CC CT TT 0. A CC result indicates you have a gifted form of the gene that makes a protein found in fast-twitch muscle fibers, and therefore The frequencies of all three genotypes, CC, CT, and TT, reported in patients were 14%, 65% and 21% and in healthy controls 18%, 73% and 9% respectively. (A) Myosin heavy chain slow isoform and myosin heavy chain fast isoform protein levels in muscle protein lysates (CC/II: n = 6, CT/IN: n = 6 and TT/NN: n = 6) measured by immunoblot analysis. CKM / Hpy 188 I. tion’) has been shown to be associated with optimum race distance in Thoroughbred horses in a number of studies [16–20]. 6% vs. , race, geographic region)? IL28B genotypes CC, CT, TT, How clinically relevant is the association? IL28B genotypes CC, CT, TT and more. 9%, 33. 46%, respectively. The ACTN3 577 RR genotype means that you have two copies of the functioning ACTN3 gene (rs1815739 CC). The investigation of VDR Fokl (rs2228570) was conducted on 150 samples (control (75 healthy women) and diseased women (75 diseased with autoimmune thyroiditis)) patients from the Adjara (Georgia Jun 15, 2019 · Results: The distribution of genotype of CC, CT TT and T allele of MTHFR C677T, genotype of AA and C allele of MTHFR A1298C, and genotype of AA, AG and G allele of MTRR A66G were different between cases and controls (all p were < 0. 71 μmol/L) (P < 0. We have established three conditionally immortalised skeletal muscle cell lines that represent an in vitro model of Thoroughbred horse skeletal muscle MSTN genotypes CC/II, CT/IN and TT/NN. Jul 31, 2022 · For the C147T SNP, the frequencies of the CC, CT, and TT genotypes were 90. Jan 1, 2012 · For each measure, horses with the C/C and C/T genotypes outperformed T/T horses, indicating the requirement for at least one C-allele to improve speed. 0 had a significantly increased risk of NHL if they carried BRCA1 (rs799917) CT/TT genotypes (OR=1. 68 pg/ml vs 14. Overall, 76% (425/557) of AMD patients had the CC or CT genotype (Table 6). The rs429538 CT and CC genotypes increased the risk of DAT by 2. 4–3. TG/GG, OR=2. 010). qPCR was used to measure gene expression levels of three genes: MYH7 (A Dec 9, 2014 · The association between the lupus anticoagulant (LA) activity and FXII activity was examined. 9% in CC and 77. . Folate is an essential cofactor in the one‐carbon metabolism pathway and is necessary in amino acid (A) Myosin heavy chain slow isoform and myosin heavy chain fast isoform protein levels in muscle protein lysates (CC/II: n = 6, CT/IN: n = 6 and TT/NN: n = 6) measured by immunoblot analysis. 55601543C>T CC CT TT C T 0. 02–2. 64 0. Penetrance is the proportion of individuals showing a specified genotype in their phenotype under a given set of environmental conditions. 0% versus 84. The frequency of the CC, CT and TT genotypes and the FXII activity were also compared between the patients and controls. The behavioral characteristics of horses vary depending on the breed, age, and sex. The presented results of the Dec 12, 2017 · The mutation rates of CC, CT, and TT genotypes were 15. TT); (D) Dominant model (CC+CT vs. The CT/TT genotypes and T allele were overrepresented among the CRC cases. Hcy levels in patients with MTHFR CC, CT, and TT genotypes were increased (15. 2 ± 0. 7% vs. 8; 95% CI, 1. 37). Individuals with CT or TT genotypes have increased dopamine activity. 8 The prevalence of the Chinese hypertensive MTHFR Jul 1, 2022 · Horses with the GG and GA genotypes had significantly higher plasma concentrations of DA compared to horses with the AA genotype for the G292A gene. 588268 T>C bred horses, Equine the α A-globin gene expression levels between pigeons carrying different g. 68%, all three horses with AA genotypes were identified as Thoroughbreds. People with the CC genotype have a stronger immune response to HCV infection than people with the CT or TT genotypes (called non-CC genotypes). 2% of the tested population. as 40. 5%, 49. 4%, OR 0. 8% and 6. In conclusion, 10 new physical fitness-related genotypes were identified among the 68 genotypes examined, that is, CNR1 (rs1049353; GG), LEP (rs7799039; AA+AG), HHEX (rs1111875; TT), GC (rs16847015; TG+GG), LRP5 (rs4988300; GG+GT), NPY2R (rs2880415; CT+CC), PPY (rs231472; GG), UCP2 (rs660339; CT+TT), CDKN2B (rs10811661; AA+AG), and ADIPOQ Download scientific diagram | Skeletal muscle fibre type proportions among MSTN genotype (CC/II, CT/IN, TT/NN) horses. 18 (CC), 35. 001). Assessment of fat content are total cholesterol and Trigeliserida. 8%). 65), but suggested that there was a significant difference between the slopes of CARS-M vs RBC folate for MTHFR CC and TT (p = 0. 2%) patients and the IL28b genotype CC/CT/TT distribution was 61. 05）。 Oct 14, 2020 · Results: The frequencies of CC, CT, and TT genotypes were 19. Study with Quizlet and memorize flashcards containing terms like How does this gene predict efficacy or toxicity of drug therapy? Which drug? How strong is the association? IL28B genotypes CC, CT, TT, Is the gene more prevalent in certain patient populations (e. CONCLUSION: Our data provided strong evidence that the GNAS1 T393C genetic polymorphism influenced the prognosis in advanced non-small lung cancer with a worse outcome for C Controls showed 74% CC and 26% CT genotypes, but no AMPD1 TT genotype was detected. The prevalence of CD14-159 TT and CT genotypes were associated with increased risk of brucellosis [odds ratio Nov 30, 2017 · The ‘add back’ of ubiquinone to the assays removed any difference in genotype variation, suggesting that endogenous CoQ production in TT/NN horses is lower than in CT/IN and CC/NN horses. 1). 4%, 46. 58 0. Conclusions Jul 31, 2022 · Dopamine (DA) is known to be a key modulator of animal behaviors. 825). Animal weight was also shown to be positively associated (P < 0. 3 times, respectively. , What was the average novelty-seeking score for individuals with the CC genotype?, What does the CC genotype refer to? How does it differ from the CT or TT genotypes? and more. 32%, 9. 7, 488. ,using cholesterol method: CHOD-PAP (Cholesterol A, B, C. 127-2. 5%, 48. Post-hoc analyses suggested no significant differences between the slopes (CARS-M vs RBC Folate) for MTHFR CC and CT genotypes (p = 0. 71 μmol/L and 17. Heterozygous horses accounted for 37%, while homozygous TT horses accounted for 3. 010 for T vs. 8% CC, 54% CT, 8. 021, OR = 0. 05). The T allele (blue curve) is indicated by the FAM dye Feb 8, 2022 · We found that CYP3A4 (rs3735451) was significantly correlated with blood concentration of HCQ and its metabolites by adjusting for the time of administration, and the mean blood concentrations of HCQ, DHCQ, and DCQ in patients with CC, CT, and TT genotypes is higher than those of other genotypes, with the blood concentration of HCQ and its main The MTHFR rs1801133 TT and CT genotype had increased risk for CSVD, and the OR was higher in the TT genotype than in the CT genotype (2. 03) genotypes, and between the slopes of CARS-M vs RBC folate for MTHFR CT and TT Jan 10, 2014 · The associations of alleles with the response patterns were predicted. 57, 95 % CI 1. 91%, 1. Percentages of the genotypes (CC, TT, CT) in the control and tuberculosis groups. 004 respectively. 96 ± 4. 56; CC vs. 91 (95 % CI 2. 2009) of investigating the GNB3 rs5443 polymorphism, we performed odds ratio analysis by comparing CC genotypes with the combined CT and TT genotypes. 22, p value (two-tailed) = 0. We found there was no significant association Nov 20, 2020 · Frequency of the CC, CT and TT genotypes was 65. Some genotypes contribute to an individual’s observable traits, called the phenotype. 50 (CC), 26. The MTHFR and MTHFD genotype distributions in the cases and controls were shown in Table III. 95; CC vs. TT); (C) Heterozygote comparison (CT vs. There were significant differences in genotype distribution between the groups (P<0. 85 ± 6. The discovery highlighted the importance The pooled analysis showed that TT genotype of MTHFR gene is more common in stroke patients than in controls when compared to CC + CT genotypes (p = 0. 43%. 11-7. 473). 646, 95 % confidence interval = 1. 5%; and 8. 37–5. 18 μmol/L, and 21. 66493737C > T/SINE insertion 227 bp polymorphism). 8% Oct 1, 2010 · Myostatin, also known as growth differentiation factor 8 (GDF8), belongs to the TGF- β superfamily of proteins. 02 and P = 0. 04 ± 5. 59 μmol/L, 16. 69, 0. The allelic frequency of mutant T was 55. Analysis was performed for association with CFH genotypes (CC/CT) and alleles; no significant difference in the frequency of CFH genotypes or alleles was found between the two groups (data not shown). Compared with CC, CT/TT enhanced the risk of CRC (odds ratio = 1. 2% 0. 1%, 29. Frequency of the CC genotype was lower and that of the CT+TT genotype higher in the T2DM with cIMT group. 6% The patients included thirty-five CC; twenty-four CT; and nine TT genotypes for ANKK1 and twenty-three GG; thirty GT; and fifteen TT genotypes for DRD2 (See Table 1). CT/TT, OR=1. MTHFR677CT genotype, MTHFR677TT genotype, smoking, family history of Mar 4, 2022 · CC horses are most suited to sprint racing, CT horses excel in middle distance races, and TT horses are best for longer distance racing requiring stamina. 91 ± 8. 9. Whether the distributions of genotypes among controls conformed to Hardy-Weinberg equilibrium (HWE) was determined by using a chi-square test and p < 0. C alleles) and IS (P = 0. Correlation analysis indicated that the IAT score was positively correlated with the Y-BOCS and BIS scores for the CC+CT genotype in patients with IAD. Mar 1, 2023 · To develop an in vitro system for functional experiments we established three novel equine skeletal muscle cell lines reflecting the variation in phenotype associated with MSTN genotype (CC/II, CT/IN and TT/NN for SNP g. XRCC2 protein expression of CRC patients with CT/TT genotypes was significantly higher than that of the patients with CC genotype (χ (2) = 4. 887, P Jul 8, 2024 · Distribution of MTHFR C677T genotypes and alleles. 792; P TT/CT = 0. Jun 5, 2014 · Previous findings on genotype 1-infected patients have shown association of CC genotype with spontaneous clearance and CT and TT genotypes with viral persistence, chronic liver disease or liver Nov 1, 2021 · Regarding rs7903146 SNP, CT and TT genotypes were more prominent among GDM in comparison to the control group; CT carriers among the GDM group were 46. 025). 4), ERCC2 (rs13181) AA genotype (OR=2. CC, adjusted OR=0. Of these, 4. Apr 1, 2014 · The SVR rate was significantly higher in patients with the CC genotype of IL28B than in those with non-CC genotypes (CT and TT): OR = 3. 0001) with genotype, as animals of the TT, CT and CC genotypes weighed 484. 7, 95%CI:1. Results presented with mean ± SEM, p-values where shown Horses with the C / T heterozygous genotype are more versatile and are adapted to mid-range racing. 1% vs 51. Val432Ile variant (g. 6% and 13%, respectively. 74 ± 13. 008, OR TT/CC = 1. 014 for CT/TT vs. 884), whereas there was no significant difference between patients with the CC genotype or CT genotype (P = 0. 34) appeared to have a higher SVR rate than those with HCV2/3 (TT vs. However, the observation of an The samples used were distributed in three genotypes (5 CC, 5 CT and 5 TT). 4%, and 5. Conversely, African-American patients had a higher frequency of IL28B genotype TT compared to CC and CT, 31% vs. Moreover, the DA receptor genotypes are also related to horse behaviors. 0 ± 0. Gene expression was normalised to HPRT using the ΔΔCt method. 53% (TT) in the control subjects, with the difference being statistically Minimal allele frequency was 0. 66493737C > T/SINE insertion 227 bp polymorphisms [49] have variable metabolic and functional May 18, 2018 · In one study of 81 Thoroughbreds (Rooney et al. Statistically signifi cant (p = 0. Additionally, the SNP has been observed to have an effect on the body composition of Thoroughbred horses after a period of training, with CC genotype horses having a significantly greater body mass than CT or TT horses [21]. Moderate hyperhomocysteinemia‐induced low folate status is an independent risk factor for cardiovascular disease, dementia, and depression. 48. 003) higher T Horses with different MSTN genotypes, assigned as CC/II, CT/IN and TT/NN for the combined SNP g. It was revealed that the "pathological" genotypes (CC+CT) of the aldosterone synthase gene C-344T polymorphism were significantly more frequent in patients as with normal body weight and with The subjects with CT/TT genotypes were associated with decreased risk of CHD (P = 0. In a case-control study conducted by Xie et al. 6%, and 26. 13 0. 053–1. The differences between CC and TT pigeons were statistically significant (p = 0. In Thoroughbreds, two Dec 1, 2019 · Fig. 79 (CT) and 35. Individuals with the CC and CT genotypes had lower racing perfor-mance than TT ones. 73 pg/ml vs 17. The plasma homocysteine level of the homozygous TT in individuals was significantly higher than in those with CC or CT (P < 0. CC genotypes, P = 0. 05）；观察组cc基因型频率及c等位基因频率均显著低于对照组，tt基因型频率及t等位基因频率均显著高于对照组（p<0. The ABCB1 3435 genotypes were associated with disease control rate (50% in CT, 84. 5768C>T genotypes. 007, OR TT/CT = 1. Dec 22, 2010 · In the Nurses’ Health Study (NHS), the MTHFR rs1801133 variant genotypes were associated with an increased CVD risk and there was an interaction between SHMT1 and MTHFR such that the association of the MTHFR rs1801133 CT genotype (vs. Coronary (CAD) and peripheral artery disease (PAD) were common in all groups, with no differences according to genotypes. Download scientific diagram | (A) Allele comparison(C vs. 001), while hypertensive patients with the TT genotype and T allele (21. The AGLOB CC genotype was Patients with genotype CC have been shown to have higher sustained virologic response (SVR) rates than patients with genotypes CT and TT. 0054 59. Most of the analysed horses had a TT genotype (79. 29 (CT) and 23. 5%) and heterozygotes accounted for 18. 85). g. 87% vs. ,using cholesterol method: CHOD-PAP (Cholesterol Oct 31, 2018 · Thoroughbred horses are finely-tuned athletes with a high aerobic capacity relative to skeletal muscle mass, attributable to centuries of genetic selection for speed and stamina. 2008; Hauner et al. The frequency of the common homozygote in Asian patients was high, followed by European patients and African patients. The patients were mostly Caucasian males with a mean age of 39 years. Sequenograms of CC, TT, and CT genotypes. 0402, OR = 1. Individuals with CC genotype have decreased dopamine activity. 307 vs 1. 001 Feb 1, 2021 · Compared with the CC genotype, southern cattle carried more the CT and TT genotypes. 0, 95%CI: 1. Compared to women whose BMI < 25, women with a BMI ≥ 25. Dec 12, 2014 · However, dichotomization between C-genotypes (CC + CT) and T-genotypes (TT) revealed significantly lower survival rates (2-year OS: 16%; P = 0. The non‐CC genotypes were significantly higher in non‐responders when compared to responders (67. genotypes to CT+TT genotypes (dominant model), or CC+CT to TT genotypes (recessive model). 09% in the patients, and 78. 3%, P = 0. 8% patients (n = 27/557) had undergone PDT treatments. 923). COQ4 (A) and ADCK3 (B) gene expression was determined for CC/II: n = 36, CT/IN: n = 34 and TT/NN: n = 11, performed in at least duplicate. The disease control rate of paclitaxel was also affected by a patient's sensitivity to anthracycline (anthracycline refractory versus sensitive; 50. 95%, and 30. 93%, respectively, P<0. Source publication. 85 pg/ml). In between those two genotypes is rs1815739 CT. DNA sequencing and other methods can be used to determine the genotypes at millions of locations in a genome in a single experiment. 6% and 14%, respectively (p<0. Thus, the aim of this study was to investigate the DA Nov 17, 2020 · Based on alcohol consumption, the CT and TT genotypes may reduce gastric cancer risk (TT/CT vs. 5. 17-57-26 in stroke patients. 962, P=0. Individual horse (n) with TT, TT, CC and AA genotypes, have evidenced that CC horses at SNP rs397152648 are more suitable for. Consequently, dominant and recessive models were highly significant among the GDM group in comparison to the control group. 48 ± 9. 71 (TT) in TOF patients; and 41. 5 and 1 day ago · Genotypes can also be represented by the actual DNA sequence at a specific location, such as CC, CT, TT. , 2017), it was found that 45% of the horses had CC/II, 42% had CT/IN and 13% had TT/NN. However, Eloualid’s team found no association between MTHFR 677 CT and TT genotypes and the risk of oligozoospermia in Casablanca, Morocco 14. 002) and with an increase in high-density lipoprotein cholesterol levels ( P = . Although not statistically significant, the +NAFLD group had a reduced level of CAT independently of the genotype. Although the tests described previously are all valid methods for analysis of an association study, any such study should have a prespecified analysis plan because applying all tests will increase the probability of a false-positive result. Patients carried the T allele with higher frequency than controls (73. Other types of genetic marker , such as microsatellites , can have more than two alleles, and thus many different genotypes. 23 0. Thus, the plasma concentration of DA might be used as a biomarker for the behavioral characteristics of horses. 33). Aug 1, 2020 · CC CT TT C T. 80 0. 3%, respectively. CT/TT, OR=4. Results: The IL28B rs12979860 CC genotype occurred in lower frequency in hepatitis C-virus infected patients than in healthy controls (26. The frequencies of the CC, TT, and CT genotypes of MTHFR (C677T) were 64. 8%, 11. A significant association has also been found between MSTN genotype and body composition, with C/C male horses having a significantly greater body mass-to-height ratio than C/T or T/T horses. MSTN is a highly conserved protein that acts as a negative regulator of skeletal muscle growth. 1%, respectively, in the healthy control group. 05）。两组基因型、等位基因分布比较差异有统计学意义（p<0. g. Furthermore, the association results carried out that the frequencies of genotypes (CC, CT, TT) and the value of climate parameters (mean annual temperature (T), relative humidity (RH) and temperature humidity index (THI)) were significantly correlated (P < 0. 66493737C > T/SINE insertion 227 bp polymorphisms [49] have variable metabolic and functional Feb 26, 2015 · Because selection was based on the phenotypic value of Q, the first step of selection also resulted in an environmental superiority of qualified horses for trait Q. 404, P = 0. 2–2. In single-locus analyses, the genotype frequencies of MTHFR rs1801133 C>T were 37. Hcy levels of different C677T genotypes were significantly different. , it was demonstrated that the MTHFR 677 TT genotype posed a risk for both oligozoospermia and asthenozoospermia within the Chinese Han population. qPCR was used to measure gene expression levels of three genes: MYH7 (A In the example above, the three genotypes would be CC, CT and TT. Stroke prevalence was markedly higher in genotypes CT and TT (18 and 21%) compared with CC (6%). 01). Results There were no significant differences in either the genotype distribution or allele frequency in T2DM patients with or without dyslipidemia (37. 0001. 333, p<0. 两组儿童的年龄、性别和bmi比较差异均无统计学意义（p>0. In the Han population, patients carrying alleles such as ApoE rs429358 CC have a higher incidence of excessive anticoagulation (INR > 4) than those carrying CT and TT genotypes during the initial Download scientific diagram | Skeletal muscle mitochondrial content of MSTN genotype (CC/II, CT/IN, TT/NN) horses. (CC/II, CT/IN and TT/NN for SNP g At a SNP locus of the MSTN gene, the C2361T site was identified, with three genotypes detected: CC, CT, and TT, among which CC predominated. 2% TT vs. Nov 30, 2017 · Skeletal muscle fibre type proportions among MSTN genotype (CC/II, CT/IN, TT/NN) horses. There are three IL28B subtypes (called genotypes): CC, CT, and TT. 28), p < 0. TT = homozygote with mutated alleles (shown as AA on the sequenogram). OR TT = odds of disease in an individual with the TT genotype odds of disease in an individual with the CC genotype OR CT = odds of disease in an individual with the CT genotype odds of disease in an individual with the CC genotype I OR. The authors found that CC/II horses had lower mitochondrial content and lower proportions of type I fibres, and the most IIX type of fibres, adding support to the sprint/short distance suitability of these horses. 045–1. 38. 17 and genotype frequencies were 0. 3%, respectively for the control group. The influence of MMP9 rs2250889 CC and CG genotypes (a) and MMP9 rs20544 CC and CT+TT genotypes (b) on overall survival of malignant pleural mesothelioma patients. CC genotypes; P The frequencies of genotypes (CC-CT-TT) were (%): 44-41-15 in stroke-free vs. LA was associated with reduced FXII activity. from publication: MTHFR C677T polymorphisms are associated with aberrant methylation of the IGF-2 gene in transitional AMPD1 genotypes and allele frequencies are illustrated in Fig. qPCR was used to measure gene expression levels of three genes: MYH7 (A), MYH2 (B) and MYH1 (C) Mar 1, 2023 · To develop an in vitro system for functional experiments we established three novel equine skeletal muscle cell lines reflecting the variation in phenotype associated with MSTN genotype Mar 30, 2021 · In addition, the SNPs rs69472469, rs69472470 and rs69472471, and the SNP rs782836148 at the 3′UTR, were reported as polymorphic in the literature [15,18,33,34], were homozygous in the horse MSTN gene of this study, with TT, TT, CC and AA genotypes, respectively. Mitochondrial abundance determined by the activity of citrate synthase (CS Nov 21, 2011 · Furthermore, HCV1-infected patients with a common homozygote (TT vs. 29 0. 0391). Loss of myostatin functionality causes the phenotype to appear in the form of ‘double musculature’, among others in cattle, sheep, and house mice. 5% vs. 76 ± 8. 030) for individuals miscarriage rates among the CC, CT, TT genotypes and according to the FXII activity was examined. 1%, and 8. As the method adopted in this study was similar to the previous studies (Grudell et al. Mar 2, 2018 · The three different genotypes created by ACTN3 are CC, TT, and TC. This gene alters our pleasure center, and influences initiation and motivation. 09%, and 20. Jun 26, 2016 · In the stratification analysis, XPA rs10817938 CT/CC, rs2231142 CA/AA, and rs2622621 CC genotypes of ABCG2 were predictive of significantly better prognosis in the patients with tumor Feb 1, 2016 · According to the prevailing theory about the genetic background to lactose intolerance, there are three genotypes but only two adult physiological phenotypes: lactase persistence in individuals with the CT and TT genotypes and lactase non-persistence in individuals with the CC genotype. 54% and TT carriers were 37. Sep 7, 2023 · We also presented the CAT levels in the +NAFLD and −NAFLD groups according to the genotypes (CC, CT and TT) and alleles (CC, CT + TT), for which the data are shown in Figures S1 and S2 in the Supplementary Materials. In addition, significant gene expression variation in two key CoQ synthesis pathway genes (COQ4 and ADCK3) was associated with MSTN genotype. The plasma Hcy levels of different genotypes showed the tendency of the TT genotype > CT genotype > CC genotype (19. 27, and 0. 2% TT genotypes. Multicomponent Plot images in Real-Time PCR of the CC, CT, and TT genotypes of the ACTN3 rs1815739 polymorphism. 409, 95% CI: 1. 5% in TT: CT versus CC, P = 0. The LDLR TT genotype as well as LDLR T allele was associated with increased susceptibility to CAD in Indian patients.